Novel approaches to global mining of aberrantly methylated promoter sites in squamous head and neck cancer.

Abstract

OBJECTIVE Promoter hypermethylation is emerging as a promising molecular strategy for early detection of cancer. We examined promoter methylation status of 1143 cancer-associated genes to perform a global but unbiased inspection of methylated regions in head and neck squamous cell carcinoma (HNSCC). STUDY DESIGN Laboratory-based study. SETTING… (More)
DOI: 10.1016/j.otohns.2010.02.015

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