Novel anti-ulcer alpha,beta-unsaturated lactones inhibit compound 48/80-induced mast cell degranulation.

@article{Penissi2009NovelAA,
  title={Novel anti-ulcer alpha,beta-unsaturated lactones inhibit compound 48/80-induced mast cell degranulation.},
  author={A. Penissi and Mariano E Vera and M. L. Mariani and M. Rudolph and J. P. Ce{\~n}al and J. C. de Rosas and T. Fogal and C. Tonn and L. Favier and O. Giordano and R. Piezzi},
  journal={European journal of pharmacology},
  year={2009},
  volume={612 1-3},
  pages={
          122-30
        }
}
  • A. Penissi, Mariano E Vera, +8 authors R. Piezzi
  • Published 2009
  • Chemistry, Medicine
  • European journal of pharmacology
  • The present study was designed to examine the effects of a sesquiterpene lactone isolated from Artemisia douglasiana Besser (dehydroleucodine), a xanthanolide sesquiterpene isolated from Xanthium cavanillesii Schouw (xanthatin) and a semisynthetic butenolide (3-benzyloxymethyl-5H-furan-2-one) on mast cell degranulation induced by compound 48/80. Peritoneal mast cells from male adult Sprague-Dawley rats were purified in Percoll, preincubated in the presence of test lactones (dehydroleucodine… CONTINUE READING
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