Novel anti-HIV lancilactone C and related triterpenes from Kadsura lancilimba.

@article{Chen1999NovelAL,
  title={Novel anti-HIV lancilactone C and related triterpenes from Kadsura lancilimba.},
  author={Dao-feng Chen and Shuxing Zhang and Hongbing Wang and Shou-yao Zhang and Qingnan Sun and Louis M Cosentino and Kuo ‐ Hsiung Lee},
  journal={Journal of natural products},
  year={1999},
  volume={62 1},
  pages={
          94-7
        }
}
Three new triterpene lactones, lancilactones A (1), B (2), and C (3), together with the known kadsulactone A (4), were isolated from the stems and roots of Kadsura lancilimba. Their structures and stereochemistries were determined primarily from mass and NMR spectral data. Compound 3 inhibited HIV replication with an EC50 value of 1.4 microg/mL and a therapeutic index of greater than 71.4. 
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 14 CITATIONS

Similar Papers

Loading similar papers…