Novel and conventional receptors for ghrelin, desacyl-ghrelin, and pharmacologically related compounds.

Abstract

The only molecularly identified ghrelin receptor is the growth hormone secretagogue receptor GHSR1a. Its natural ligand, ghrelin, is an acylated peptide whose unacylated counterpart (UAG) is almost inactive at GHSR1a. A truncated, nonfunctional receptor, GHSR1b, derives from the same gene. We have critically evaluated evidence for effects of ghrelin… (More)
DOI: 10.1124/pr.113.008433

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@article{Callaghan2014NovelAC, title={Novel and conventional receptors for ghrelin, desacyl-ghrelin, and pharmacologically related compounds.}, author={Brid P. Callaghan and John B. Furness}, journal={Pharmacological reviews}, year={2014}, volume={66 4}, pages={984-1001} }