Novel abietane diterpenoids and aromatic compounds from Cladonia rangiferina and their antimicrobial activity against antibiotics resistant bacteria.

@article{Yoshikawa2008NovelAD,
  title={Novel abietane diterpenoids and aromatic compounds from Cladonia rangiferina and their antimicrobial activity against antibiotics resistant bacteria.},
  author={Kazuko Yoshikawa and Naoki Kokudo and Masami Tanaka and Tatsuro Nakano and Hirofumi Shibata and Naokatsu Aragaki and Tomihiko Higuchi and Toshihiro Hashimoto},
  journal={Chemical & pharmaceutical bulletin},
  year={2008},
  volume={56 1},
  pages={89-92}
}
From Cladonia rangiferina were isolated two novel abietane diterpenoids, hanagokenols A (1) and B (2). Also in this investigation, four known abitetane diterpenoids (3-6), four known labdane diterpenoids (7-10), one known isopimarane diterpenoid (11), and six known aromatic compounds were isolated. These structures were elucidated primarily through extensive NMR experiments. Hanagokenol A (1) was a unique abietane diterpene having an ether linkage between C-6 and C-18 of sugiol. Hanagokenol B… CONTINUE READING