Novel Water-Soluble Diorganyl Tellurides with Thiol Peroxidase and Antioxidant Activity.

@article{Kanda1999NovelWD,
  title={Novel Water-Soluble Diorganyl Tellurides with Thiol Peroxidase and Antioxidant Activity.},
  author={Takahiro Kanda and Lars Engman and Ian A. Cotgreave and Garth Powis},
  journal={The Journal of organic chemistry},
  year={1999},
  volume={64 22},
  pages={8161-8169}
}
Novel water-soluble diaryl tellurides, alkyl aryl tellurides, and dialkyl tellurides carrying sulfopropyl groups were prepared and found to possess potent peroxide decomposing and chain-breaking antioxidative capacity. The dilithium, disodium, dipotassium, and bis-tetramethylammonium salts of bis(4-hydroxyphenyl) telluride (4) were treated with 2.3 equiv of 1,3-propanesultone in aqueous tert-butyl alcohol to give the corresponding salts 5 of bis-O-sulfopropylated diaryl telluride. A variety of… CONTINUE READING