Novel Transgenic Rice-Based Vaccines

  title={Novel Transgenic Rice-Based Vaccines},
  author={Tatsuhiko Azegami and Hiroshi Itoh and Hiroshi Kiyono and Yoshikazu Yuki},
  journal={Archivum Immunologiae et Therapiae Experimentalis},
Oral vaccination can induce both systemic and mucosal antigen-specific immune responses. To control rampant mucosal infectious diseases, the development of new effective oral vaccines is needed. Plant-based vaccines are new candidates for oral vaccines, and have some advantages over the traditional vaccines in cost, safety, and scalability. Rice seeds are attractive for vaccine production because of their stability and resistance to digestion in the stomach. The efficacy of some rice-based… CONTINUE READING