Novel TPR-containing subunit of TOM complex functions as cytosolic receptor for Entamoeba mitosomal transport

@inproceedings{Makiuchi2013NovelTS,
  title={Novel TPR-containing subunit of TOM complex functions as cytosolic receptor for Entamoeba mitosomal transport},
  author={Takashi Makiuchi and Fumika Mi-Ichi and Kumiko Nakada-Tsukui and Tomoyoshi Nozaki},
  booktitle={Scientific reports},
  year={2013}
}
Under anaerobic environments, the mitochondria have undergone remarkable reduction and transformation into highly reduced structures, referred as mitochondrion-related organelles (MROs), which include mitosomes and hydrogenosomes. In agreement with the concept of reductive evolution, mitosomes of Entamoeba histolytica lack most of the components of the TOM (translocase of the outer mitochondrial membrane) complex, which is required for the targeting and membrane translocation of preproteins… CONTINUE READING
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