Novel Strategies for the Treatment of Chondrosarcomas: Targeting Integrins

  title={Novel Strategies for the Treatment of Chondrosarcomas: Targeting Integrins},
  author={Jui-Chieh Chen and Yi-chin Fong and Chih-Hsin Tang},
  booktitle={BioMed research international},
Chondrosarcomas are a heterogeneous group of malignant bone tumors that are characterized by the production of cartilaginous extracellular matrix. They are the second most frequently occurring type of bone malignancy. Surgical resection remains the primary mode of treatment for chondrosarcomas, since conventional chemotherapy and radiotherapy are largely ineffective. Treatment of patients with high-grade chondrosarcomas is particularly challenging, owing to the lack of effective adjuvant… CONTINUE READING
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