Novel Salmonella enterica serovar Typhimurium protein that is indispensable for virulence and intracellular replication.

@article{Straaten2001NovelSE,
  title={Novel Salmonella enterica serovar Typhimurium protein that is indispensable for virulence and intracellular replication.},
  author={Tahar van der Straaten and Angela van Diepen and Kitty M. C. Kwappenberg and Sjaak van Voorden and Kees Franken and R. Janssen and Johannes G Kusters and Donald L. Granger and Jaap Tamino van Dissel},
  journal={Infection and immunity},
  year={2001},
  volume={69 12},
  pages={7413-8}
}
Upon contact with host cells, the intracellular pathogen Salmonella enterica serovar Typhimurium promotes its uptake, targeting, and survival in intracellular niches. In this process, the bacterium evades the microbicidal effector mechanisms of the macrophage, including oxygen intermediates. This study reports the phenotypic and genotypic characterization of an S. enterica serovar Typhimurium mutant that is hypersusceptible to superoxide. The susceptible phenotype is due to a MudJ insertion… CONTINUE READING