Novel SOX9 expression during human pancreas development correlates to abnormalities in Campomelic dysplasia

Abstract

Haploinsufficiency of SOX9, which encodes a homeodomain transcription factor, results in Campomelic dysplasia. Classical features of this disorder (e.g. skeletal dysplasia and 46,XY sex reversal) are in concordance with SOX9 expression profiles during human embryonic development. We report the robust expression of SOX9 throughout the pancreas during human… (More)
DOI: 10.1016/S0925-4773(02)00145-4

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