Novel Rheumatoid Arthritis Susceptibility Locus at 22q12 Identified in an Extended UK Genome-Wide Association Study

@inproceedings{Orozco2014NovelRA,
  title={Novel Rheumatoid Arthritis Susceptibility Locus at 22q12 Identified in an Extended UK Genome-Wide Association Study},
  author={Gisela Orozco and Sebastien Viatte and John Bowes and Paul Martin and Anthony G. Wilson and Ann W Morgan and Sophia Steer and Paul Wordsworth and Lynne J. Hocking and Anne Barton and Jane Worthington and Stephen Eyre},
  booktitle={Arthritis & rheumatology},
  year={2014}
}
OBJECTIVE The number of confirmed rheumatoid arthritis (RA) loci currently stands at 32, but many lines of evidence indicate that expansion of existing genome-wide association studies (GWAS) enhances the power to detect additional loci. This study was undertaken to extend our previous RA GWAS in a UK cohort, adding more independent RA cases and healthy controls, with the aim of detecting novel association signals for susceptibility to RA in a homogeneous UK cohort. METHODS A total of 3,223 UK… CONTINUE READING