Novel Ran-RCC1 Inhibitory Peptide-Loaded Nanoparticles Have Anti-Cancer Efficacy In Vitro and In Vivo

@inproceedings{Haggag2019NovelRI,
  title={Novel Ran-RCC1 Inhibitory Peptide-Loaded Nanoparticles Have Anti-Cancer Efficacy In Vitro and In Vivo},
  author={Yusuf Ahmed Haggag and Kyle B. Matchett and Robert A Falconer and Mohammad Isreb and Jason Christopher Jones and Ahmed Moustafa Faheem and Paul A McCarron and Mohamed El-Tanani El-Tanani},
  booktitle={Cancers},
  year={2019}
}
The delivery of anticancer agents to their subcellular sites of action is a significant challenge for effective cancer therapy. Peptides, which are integral to several oncogenic pathways, have significant potential to be utilised as cancer therapeutics due to their selectivity, high potency and lack of normal cell toxicity. Novel Ras protein-Regulator of chromosome condensation 1 (Ran-RCC1) inhibitory peptides designed to interact with Ran, a novel therapeutic target in breast cancer, were… CONTINUE READING
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