Novel Properties of a Mouse γ-Aminobutyric Acid Transporter (GAT4)

@article{Karakossian2004NovelPO,
  title={Novel Properties of a Mouse γ-Aminobutyric Acid Transporter (GAT4)},
  author={Movses H. Karakossian and Shelly R. Spencer and Ana Maria Quintero G{\'o}mez and Oscar R Padilla and Ayelet Sacher and D S Loo and Nathan Alfred Nelson and Sepehr Eskandari},
  journal={The Journal of Membrane Biology},
  year={2004},
  volume={203},
  pages={65-82}
}
We expressed the mouse γ-aminobutyric acid (GABA) transporter GAT4 (homologous to rat/human GAT-3) in Xenopus laevis oocytes and examined its functional and pharmacological properties by using electrophysiological and tracer uptake methods. In the coupled mode of transport (Na+/Cl−/GABA cotransport), there was tight coupling between charge flux and GABA… CONTINUE READING