Novel Polyester-Polysaccharide Nanoparticles

@article{Lemarchand2004NovelPN,
  title={Novel Polyester-Polysaccharide Nanoparticles},
  author={Caroline Lemarchand and Patrick Couvreur and Madeleine Besnard and Dominique Costantini and Ruxandra Gref},
  journal={Pharmaceutical Research},
  year={2004},
  volume={20},
  pages={1284-1292}
}
AbstractPurpose. The aim of the present study was to develop a new type of core-shell nanoparticles from a family of novel amphiphilic copolymers, based on dextran (DEX) grafted with poly(ε–caprolactone) (PCL) side chains (PCL-DEX). Methods. A family of PCL-DEX copolymers was synthesized in which both the molecular weight and the proportion by weight of DEX in the copolymer were varied. The nanoparticles were prepared by a technique derived from emulsion-solvent evaporation, during which… 
Physico-chemical characterization of polysaccharide-coated nanoparticles.
Physicochemical characterization of self-assembled poly(∈-caprolactone) grafted dextran nanoparticles
Amphiphilic graft copolymer composed of poly(∈-caprolactone) and dextran was synthesized by ring opening polymerization of ∈-caprolactone initiated through the hydroxyl end of dextran in the presence
Influence of polysaccharide coating on the interactions of nanoparticles with biological systems.
Nanoparticles made from novel starch derivatives for transdermal drug delivery.
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