Novel Methodology for Comparing Standard-of-Care Interventions in Patients With Cancer.

  title={Novel Methodology for Comparing Standard-of-Care Interventions in Patients With Cancer.},
  author={John Frederick Hilton and Sasha Mazzarello and Dean Fergusson and Anil Abraham Joy and Andrew Robinson and Angel Arnaout and Brian Hutton and Lisa A Vandermeer and Mark Clemons},
  journal={Journal of oncology practice},
  volume={12 12},
PURPOSE The current clinical trials development and conduct process is cumbersome and expensive, with the majority of studies focusing on either the development of new agents or new indications for established agents. Unfortunately, research comparing standard-of-care interventions is rarely performed, leaving many important and practical patient-centered questions unanswered. Novel clinical trial methodologies and approaches are needed. METHODS We have identified simple key components that… CONTINUE READING
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