Novel MUC1 splice variants are expressed in cervical carcinoma.

  title={Novel MUC1 splice variants are expressed in cervical carcinoma.},
  author={Andreas Obermair and Bernd C. Schmid and Margit Stimpfl and Barbara Fasching and Oliver Preyer and Sepp Leodolter and Alexander J Crandon and Robert Zeillinger},
  journal={Gynecologic oncology},
  volume={83 2},
OBJECTIVES The MUC1 antigen can be used to identify epithelial cells from the background of hemopoietic cells. The present investigation describes patterns of overexpression of two novel MUC1 splice variants in human cervical carcinoma cell lines. METHODS RT-PCR was carried out to determine MUC1 splice variants in the cervical cancer cell lines C-4 II, C-33A, DoTc 2 4510, C-4 I, SiHa, HT3, Hs 636 T (C4-I), and HeLa. RESULTS The novel MUC1 splice variant D was expressed in all cell lines and… CONTINUE READING
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