Novel MRI Contrast Agent from Magnetotactic Bacteria Enables In Vivo Tracking of iPSC-derived Cardiomyocytes

@inproceedings{Mahmoudi2016NovelMC,
  title={Novel MRI Contrast Agent from Magnetotactic Bacteria Enables In Vivo Tracking of iPSC-derived Cardiomyocytes},
  author={Morteza Mahmoudi and Atsushi Tachibana and Andrew Goldstone and Yiping Joseph Woo and Papia Chakraborty and Kayla R. Lee and Chandler S. Foote and Stephanie Piecewicz and Joyce Cueto Barrozo and Abdul Aziz Al Wakeel and Bradley Woodward Rice and Caleb B. Bell and Phillip C Yang},
  booktitle={Scientific reports},
  year={2016}
}
Therapeutic delivery of human induced pluripotent stem cell (iPSC)-derived cardiomyocytes (iCMs) represents a novel clinical approach to regenerate the injured myocardium. However, methods for robust and accurate in vivo monitoring of the iCMs are still lacking. Although superparamagnetic iron oxide nanoparticles (SPIOs) are recognized as a promising tool for in vivo tracking of stem cells using magnetic resonance imaging (MRI), their signal persists in the heart even weeks after the… CONTINUE READING
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