Novel MITF targets identified using a two‐step DNA microarray strategy

@article{Hoek2008NovelMT,
  title={Novel MITF targets identified using a two‐step DNA microarray strategy},
  author={Keith S. Hoek and Natalie C. Schlegel and Ossia M Eichhoff and Daniel S. Widmer and Christian Praetorius and Steingr{\'i}mur Einarsson and Sigr{\'i}dur Valgeirsd{\'o}ttir and Kristin Bergsteinsdottir and Alexander Schepsky and Reinhard Dummer and Eir{\'i}kur Steingr{\'i}msson},
  journal={Pigment Cell \& Melanoma Research},
  year={2008},
  volume={21}
}
Malignant melanoma is a chemotherapy‐resistant cancer with high mortality. Recent advances in our understanding of the disease at the molecular level have indicated that it shares many characteristics with developmental precursors to melanocytes, the mature pigment‐producing cells of the skin and hair follicles. The development of melanocytes absolutely depends on the action of the microphthalmia‐associated transcription factor (MITF). MITF has been shown to regulate a broad variety of genes… Expand
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