Novel Insights into DNA Methylation Features in Spermatozoa: Stability and Peculiarities

@inproceedings{Krausz2012NovelII,
  title={Novel Insights into DNA Methylation Features in Spermatozoa:
Stability and Peculiarities},
  author={C Krausz and Juan Sandoval and Sergi Sayols and Chiara Chianese and Claudia Giachini and Holger Heyn and Manel Esteller},
  booktitle={PloS one},
  year={2012}
}
Data about the entire sperm DNA methylome are limited to two sperm donors whereas studies dealing with a greater number of subjects focused only on a few genes or were based on low resolution arrays. This implies that information about what we can consider as a normal sperm DNA methylome and whether it is stable among different normozoospermic individuals is still missing. The definition of the DNA methylation profile of normozoospermic men, the entity of inter-individual variability and the… CONTINUE READING
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