Novel Insights into Breast Cancer Genetic Variance through RNA Sequencing

@inproceedings{Horvath2013NovelII,
  title={Novel Insights into Breast Cancer Genetic Variance through RNA Sequencing},
  author={Anelia Horvath and Suresh Babu Pakala and Prakriti Mudvari and Sirigiri Divijendra Natha Reddy and Kazufumi Ohshiro and Sandra Casimiro and Ricardo Tadeu Faria Pires and Suzanne A W Fuqua and Masakazu Toi and Lu{\'i}s Duarte Costa and Sujit S. Nair and Saraswati Vaidyanathan Sukumar and Rakesh Kumar},
  booktitle={Scientific reports},
  year={2013}
}
Using RNA sequencing of triple-negative breast cancer (TNBC), non-TBNC and HER2-positive breast cancer sub-types, here we report novel expressed variants, allelic prevalence and abundance, and coexpression with other variation, and splicing signatures. To reveal the most prevalent variant alleles, we overlaid our findings with cancer- and population-based datasets and validated a subset of novel variants of cancer-related genes: ESRP2, GBP1, TPP1, MAD2L1BP, GLUD2 and SLC30A8. As a proof-of… CONTINUE READING
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