Novel Inhibitor Design for Hemagglutinin against H1N1 Influenza Virus by Core Hopping Method

@article{Li2011NovelID,
  title={Novel Inhibitor Design for Hemagglutinin against H1N1 Influenza Virus by Core Hopping Method},
  author={Xiao-bo Li and Shu-Qing Wang and Wei-Ren Xu and Run-Ling Wang and Kuo-Chen Chou},
  journal={PLoS ONE},
  year={2011},
  volume={6}
}
The worldwide spread of H1N1 avian influenza and the increasing reports about its resistance to the current drugs have made a high priority for developing new anti-influenza drugs. Owing to its unique function in assisting viruses to bind the cellular surface, a key step for them to subsequently penetrate into the infected cell, hemagglutinin (HA) has become one of the main targets for drug design against influenza virus. To develop potent HA inhibitors, the ZINC fragment database was searched… Expand

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