Novel HPV-6 variants of human papillomavirus causing recurrent respiratory papillomatosis in southern Africa.

@article{Combrinck2012NovelHV,
  title={Novel HPV-6 variants of human papillomavirus causing recurrent respiratory papillomatosis in southern Africa.},
  author={Catharina E Combrinck and R Y Seedat and Charles Randall and Yolande Roodt and Felicity J Burt},
  journal={Epidemiology and infection},
  year={2012},
  volume={140 6},
  pages={1095-101}
}
There is currently no information regarding the genetic diversity of HPV-6 variants circulating in South Africa. The aim of this study was to determine the HPV-6 variants affecting patients with recurrent respiratory papillomatosis, to determine whether mutations correlate with disease severity and identify molecular determinants of virulence with prognostic relevance. HPV-6 variants were identified based on genome changes within the 712-991 bp region encompassing the non-coding region (URR) of… CONTINUE READING