Novel HMGB1-inhibiting therapeutic agents for experimental sepsis.

@article{Wang2009NovelHT,
  title={Novel HMGB1-inhibiting therapeutic agents for experimental sepsis.},
  author={Haichao Wang and Mary Frances Ward and Andrew E. Sama},
  journal={Shock},
  year={2009},
  volume={32 4},
  pages={348-57}
}
Sepsis refers to a systemic inflammatory response syndrome resulting from a microbial infection. The inflammatory response is partly mediated by innate immune cells (such as macrophages, monocytes, and neutrophils), which not only ingest and eliminate invading pathogens but also initiate an inflammatory response by producing early (e.g., TNF and IFN-gamma… CONTINUE READING