Novel HLA-DRB1 alleles revealed by sequencing based typing, DRB1*04053 and DRB1*1143.

Abstract

We report the discovery of two HLA-DRB1 alleles by sequencing based typing (SBT). DRB1*04053 differs from previously reported DRB1 alleles by a single synonymous nucleotide substitution, resulting in a unique polymorphism at codon 93. DRB1*1143 differs from previously identified DRB1 alleles by a single non-synonymous nucleotide substitution, resulting in a polymorphism observed in other DRB1 and DRB3 alleles1.

Cite this paper

@article{Greville2002NovelHA, title={Novel HLA-DRB1 alleles revealed by sequencing based typing, DRB1*04053 and DRB1*1143.}, author={Warwick D Greville and Gavin B Chapman and J P Hogbin and Heather Dunckley}, journal={Tissue antigens}, year={2002}, volume={59 4}, pages={347-9} }