Novel Genetic Loci Associated With Retinal Microvascular Diameter.

  title={Novel Genetic Loci Associated With Retinal Microvascular Diameter.},
  author={Richard A. Jensen and Xueling Sim and Albert Vernon Smith and Xiaohui Li and J{\'o}hanna Jakobsd{\'o}ttir and Ching-Yu Cheng and Jennifer A Brody and Mary Frances Cotch and Barbara Mcknight and Ronald Klein and Jie Jin Wang and Annette Kifley and T. B. Harris and Lenore J. Launer and Kent D. Taylor and Barbara E. K. Klein and Leslie J. Raffel and Xiang Li and M. Arfan Ikram and Caroline C W Klaver and Sven J van der Lee and Unal Mutlu and Albert Hofman and Andr{\'e} G. Uitterlinden and Chunyu Liu and Aldi Kraja and P Mitchell and Vilmundur Gudnason and Jerome I Rotter and Eric Boerwinkle and Cornelia M van Duijn and Bruce M. Psaty and Tien Yin Wong},
  journal={Circulation. Cardiovascular genetics},
  volume={9 1},
BACKGROUND There is increasing evidence that retinal microvascular diameters are associated with cardiovascular and cerebrovascular conditions. The shared genetic effects of these associations are currently unknown. The aim of this study was to increase our understanding of the genetic factors that mediate retinal vessel size. METHODS AND RESULTS This study extends previous genome-wide association study results using 24 000+ multiethnic participants from 7 discovery cohorts and 5000+ subjects… CONTINUE READING
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