Novel GM-CSF-based vaccines: One small step in GM-CSF gene optimization, one giant leap for human vaccines.

@article{Yu2016NovelGV,
  title={Novel GM-CSF-based vaccines: One small step in GM-CSF gene optimization, one giant leap for human vaccines.},
  author={Ting-Wei Yu and Ho-Yen Chueh and Ching-Chou Tsai and C T Lin and Jiantai Timothy Qiu},
  journal={Human vaccines & immunotherapeutics},
  year={2016},
  volume={12 12},
  pages={3020-3028}
}
Granulocyte macrophage-colony stimulating factor (GM-CSF) is a potent immunomodulatory cytokine that is known to facilitate vaccine efficacy by promoting the development and prolongation of both humoral and cellular immunity. In the past years we have generated a novel codon-optimized GM-CSF gene as an adjuvant. The codon-optimized GM-CSF gene significantly… CONTINUE READING