Novel GABAergic circuits mediate the reinforcement-related signals of striatal cholinergic interneurons

@inproceedings{English2011NovelGC,
  title={Novel GABAergic circuits mediate the reinforcement-related signals of striatal cholinergic interneurons},
  author={Daniel F. English and Osvaldo Ib{\'a}{\~n}ez-Sandoval and Eran Stark and Fatuel Tecuapetla and Gy{\"o}rgy Buzs{\'a}ki and Karl Deisseroth and James M Tepper and Tibor Ko{\'o}s},
  booktitle={Nature Neuroscience},
  year={2011}
}
Neostriatal cholinergic interneurons are believed to be important for reinforcement-mediated learning and response selection by signaling the occurrence and motivational value of behaviorally relevant stimuli through precisely timed multiphasic population responses. An important problem is to understand how these signals regulate the functioning of the neostriatum. Here we describe the synaptic organization of a previously unknown circuit that involves direct nicotinic excitation of several… CONTINUE READING
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