Novel Epigenetic CREB-miR-630 Signaling Axis Regulates Radiosensitivity in Colorectal Cancer


BACKGROUND miR-630 has been reported to be a modulator of several cancers, but the mechanism by which is it influences radioresistance remains unknown. We aimed to identify the molecular function of miR-630 and its regulatory mechanism in colorectal cancer (CRC) cell lines. METHODOLOGY Overexpression and loss-of-function analyses of miR-630 were performed… (More)
DOI: 10.1371/journal.pone.0133870


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