Novel Drug Delivery System Based on Docetaxel-Loaded Nanocapsules as a Therapeutic Strategy Against Breast Cancer Cells

@inproceedings{SnchezMoreno2012NovelDD,
  title={Novel Drug Delivery System Based on Docetaxel-Loaded Nanocapsules as a Therapeutic Strategy Against Breast Cancer Cells},
  author={Paola S{\'a}nchez-Moreno and Houria Boulaiz and Juan Luis Ortega-Vinuesa and Jos{\'e} Manuel Peula-Garc{\'i}a and A. Ar{\'a}nega},
  booktitle={International journal of molecular sciences},
  year={2012}
}
In the field of cancer therapy, lipid nanocapsules based on a core-shell structure are promising vehicles for the delivery of hydrophobic drugs such as docetaxel. The main aim of this work was to evaluate whether docetaxel-loaded lipid nanocapsules improved the anti-tumor effect of free docetaxel in breast cancer cells. Three docetaxel-loaded lipid nanocapsules were synthesized by solvent displacement method. Cytotoxic assays were evaluated in breast carcinoma (MCF-7) cells treated by the… CONTINUE READING
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