Novel DNA binding by a basic helix-loop-helix protein. The role of the dioxin receptor PAS domain.

@article{ChapmanSmith2006NovelDB,
  title={Novel DNA binding by a basic helix-loop-helix protein. The role of the dioxin receptor PAS domain.},
  author={Anne Chapman-Smith and Murray L. Whitelaw},
  journal={The Journal of biological chemistry},
  year={2006},
  volume={281 18},
  pages={12535-45}
}
Central issues surrounding the basic helix-loop-helix (bHLH) superfamily of dimeric transcription factors concern how specificity of partner selection and DNA binding are achieved. bHLH proteins bind DNA through the basic sequence that is contiguous with a helix-loop-helix dimerization domain. For the two subgroups within the family, dimerization is further… CONTINUE READING