Novel Concept of a Heart-Gut Axis in the Pathophysiology of Heart Failure

Abstract

Patients with heart failure (HF) have structural and functional changes of the gut as a result of microcirculatory disturbances. A disrupted gut epithelial barrier may lead to translocation of microbial products into systemic circulation, possibly aggravating HF by inducing inflammatory responses. Gut microbiota play an essential role in the maintenance of… (More)
DOI: 10.4070/kcj.2017.0028

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