Novel Anticancer Platinum(IV) Complexes with Adamantylamine: Their Efficiency and Innovative Chemotherapy Strategies Modifying Lipid Metabolism

@article{Kozubk2008NovelAP,
  title={Novel Anticancer Platinum(IV) Complexes with Adamantylamine: Their Efficiency and Innovative Chemotherapy Strategies Modifying Lipid Metabolism},
  author={Alois Kozub{\'i}k and Alena Hyr{\vs}lov{\'a} Vaculov{\'a} and Karel Sou{\vc}ek and Jan Vondr{\'a}{\vc}ek and Jaroslav Tur{\'a}nek and Jiřina Hofmanov{\'a}},
  journal={Metal-Based Drugs},
  year={2008},
  volume={2008},
  pages={ 704 - 713}
}
The impressive impact of cisplatin on cancer on one side and severe side effects, as well as the development of drug resistance during treatment on the other side, were the factors motivating scientists to design and synthesize new more potent analogues lacking disadvantages of cisplatin. Platinum(IV) complexes represent one of the perspective groups of… CONTINUE READING