Novel Anti-Glycan Antibodies Related to Inflammatory Bowel Disease Diagnosis and Phenotype

@article{Seow2009NovelAA,
  title={Novel Anti-Glycan Antibodies Related to Inflammatory Bowel Disease Diagnosis and Phenotype},
  author={C. Seow and J. Stempak and W. Xu and H. Lan and A. Griffiths and G. Greenberg and A. Steinhart and N. Dotan and M. Silverberg},
  journal={The American Journal of Gastroenterology},
  year={2009},
  volume={104},
  pages={1426-1434}
}
OBJECTIVES:We sought to evaluate whether two novel immunoglobulin A (IgA) cell wall polysaccharide antibodies, anti-laminarin (anti-L) and anti-chitin (anti-C), aid in the diagnosis and phenotype differentiation of Crohn's disease (CD) and ulcerative colitis (UC).METHODS:A cohort of 818 individuals with inflammatory bowel disease (IBD; 517 CD and 301 UC) from two IBD tertiary referral centers, with median ages of 33 and 39 years, respectively, and disease duration of 8.9 years, were phenotyped… Expand
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  • A. Kuna
  • Medicine
  • Biochemia medica
  • 2013
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