Novel 3D porous multi-phase composite scaffolds based on PCL, thermoplastic zein and ha prepared via supercritical CO2 foaming for bone regeneration

@article{Salerno2010Novel3P,
  title={Novel 3D porous multi-phase composite scaffolds based on PCL, thermoplastic zein and ha prepared via supercritical CO2 foaming for bone regeneration},
  author={A. Salerno and S. Zeppetelli and E. Maio and S. Iannace and P. Netti},
  journal={Composites Science and Technology},
  year={2010},
  volume={70},
  pages={1838-1846}
}
Abstract The aim of this study was the design of novel biodegradable porous scaffolds for bone tissue engineering (bTE) via supercritical CO 2 (scCO 2 ) foaming process. The porous scaffolds were prepared from a poly(e-caprolactone)-thermoplastic zein multi-phase blend w/o interdispersed hydroxyapatite particles (HA) and the porous structure achieved via the scCO 2 foaming technology. The control of scaffolds porosity was obtained by modulating materials formulation and foaming temperature ( T… Expand

Figures and Tables from this paper

Formation of porous HPCL/LPCL/HA scaffolds with supercritical CO2 gas foaming method.
Preparation and characterization of aligned porous PCL/zein scaffolds as drug delivery systems via improved unidirectional freeze-drying method.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 33 REFERENCES
Design of porous polymeric scaffolds by gas foaming of heterogeneous blends
Engineering of Foamed Structures for Biomedical Application
Preparation and characterization of polycaprolactone-chitosan composites for tissue engineering applications
Fabrication of three-dimensional polycaprolactone/hydroxyapatite tissue scaffolds and osteoblast-scaffold interactions in vitro.
Hydroxyapatite and gelatin composite foams processed via novel freeze-drying and crosslinking for use as temporary hard tissue scaffolds.
Mechanical properties and in vitro biocompatibility of porous zein scaffolds.
Control of pore size and structure of tissue engineering scaffolds produced by supercritical fluid processing.
A poly(lactide-co-glycolide)/hydroxyapatite composite scaffold with enhanced osteoconductivity.
Evaluation of the zein/inorganics composite on biocompatibility and osteoblastic differentiation.
Open-pore biodegradable foams prepared via gas foaming and microparticulate templating.
...
1
2
3
4
...