• DOI:10.1016/0013-4694(58)90073-7
Corpus ID: 34839238

Note on a possible correspondence between the scotomas of migraine and spreading depression of Leão.

@article{Milner1958NoteOA,
  title={Note on a possible correspondence between the scotomas of migraine and spreading depression of Le{\~a}o.},
  author={P. Milner},
  journal={Electroencephalography and clinical neurophysiology},
  year={1958},
  volume={10 4},
  pages={
          705
        }
}

• P. Milner
• Published 1958
• Psychology, Medicine
• Electroencephalography and clinical neurophysiology

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Abstract By plotting his own scotomas at regular intervals during migraine attacks, Lashley came to the conclusion that a disturbance was advancing at about 3 mm/min. over the visual cortex. The apparent nature of the disturbance, and its rate of advance, correspond closely to those of a spreading depression observed by Leao in the cortical activity of rabbits, cats and monkeys. If these two phenomena are indeed related, the fact may suggest a means of improving migraine therapy.