Notch signaling is required for maintaining stem-cell features of neuroprogenitor cells derived from human embryonic stem cells

@inproceedings{Woo2008NotchSI,
  title={Notch signaling is required for maintaining stem-cell features of neuroprogenitor cells derived from human embryonic stem cells},
  author={Sun-Mi Woo and Janghwan Kim and Hyo-Won Han and Jung-Il Chae and Mi-Young Son and Sunwha Cho and Hyung Min Chung and Y Han and Yong Kook Kang},
  booktitle={BMC Neuroscience},
  year={2008}
}
Studies have provided important findings about the roles of Notch signaling in neural development. Unfortunately, however, most of these studies have investigated the neural stem cells (NSCs) of mice or other laboratory animals rather than humans, mainly owing to the difficulties associated with obtaining human brain samples. It prompted us to focus on… CONTINUE READING