Notch signaling influences neuroprotective and proliferative properties of mature Müller glia.

@article{Ghai2010NotchSI,
  title={Notch signaling influences neuroprotective and proliferative properties of mature M{\"u}ller glia.},
  author={Kanika Ghai and Christopher Paul Zelinka and Andy J Fischer},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2010},
  volume={30 8},
  pages={3101-12}
}
Notch signaling is known to play important roles during retinal development. Recently, Notch signaling has been shown to be active in proliferating Müller glia in acutely damaged chick retina (Hayes et al., 2007). However, the roles of Notch in mature, undamaged retina remain unknown. Thus, the purpose of this study was to determine the role of the Notch-signaling pathway in the postnatal retina. Here we show that components of the Notch-signaling pathway are expressed in most Müller glia at… CONTINUE READING