Notch: A multi-functional integrating system of microenvironmental signals.


The Notch signaling cascade is an evolutionarily ancient system that allows cells to interact with their microenvironmental neighbors through direct cell-cell interactions, thereby directing a variety of developmental processes. Recent research is discovering that Notch signaling is also responsive to a broad variety of stimuli beyond cell-cell interactions… (More)
DOI: 10.1016/j.ydbio.2016.08.023


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