Not your father's planarian: a classic model enters the era of functional genomics

  title={Not your father's planarian: a classic model enters the era of functional genomics},
  author={P. Newmark and A. Alvarado},
  journal={Nature Reviews Genetics},
  • P. Newmark, A. Alvarado
  • Published 2002
  • Biology, Medicine
  • Nature Reviews Genetics
  • Freshwater planarians were a classic model for studying the problems of development and regeneration. However, as attention shifted towards animals with more rigid developmental processes, the planarians, with their notoriously plastic ontogeny, declined in significance as a model system. This trend was exacerbated with the introduction of genetic and molecular approaches, which did not work well in planarians. More recently, the heightened interest in stem-cell biology, along with the… CONTINUE READING

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