Not all stress is equal: CREB is not necessary for restraint stress reinstatement of cocaine-conditioned reward.

Abstract

Stress elicits relapse to cocaine seeking in humans and in animal models. Cyclic AMP response element binding protein (CREB) is required for swim stress-induced reinstatement of cocaine conditioned place preference. However, the role of CREB in other stress-induced reinstatement models has not been examined. To determine whether CREB is required across… (More)
DOI: 10.1016/j.bbr.2013.02.026

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