Norwalk virus assembly and stability monitored by mass spectrometry.

  title={Norwalk virus assembly and stability monitored by mass spectrometry.},
  author={Glen K Shoemaker and Esther van Duijn and Sue E. S. Crawford and Charlotte Uetrecht and Marian Baclayon and Wouter H. Roos and Gijs J. L. Wuite and Mary K. Estes and B. V. Venkataram Prasad and Albert J. R. Heck},
  journal={Molecular & cellular proteomics : MCP},
  volume={9 8},
Viral capsid assembly, in which viral proteins self-assemble into complexes of well defined architecture, is a fascinating biological process. Although viral structure and assembly processes have been the subject of many excellent structural biology studies in the past, questions still remain regarding the intricate mechanisms that underlie viral structure, stability, and assembly. Here we used native mass spectrometry-based techniques to study the structure, stability, and assembly of Norwalk… CONTINUE READING
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