Nortriptyline in Enuresis in ' Children with Specif , Ic Gas - Chromatograph Ic Determination O , F Steady - State Serum Levels

  • NORTRIPTYLINE IN ENURESIS
  • Published 2011

Abstract

Since MacLean's (1960) original report, the tricyclic anti-depressant drugs have been studIed extensively in the treatment of nocturnal enuresis. Most authors have found them beneficial, including Mariuz and WaIters (1963), Treffert (1964), Noack (1964), Alderton (1965); Ice, Daus and Smith (1966), Yodfat (1966), Thomsen, Reid and Hebeler (1967), Agarwala and Heycock (1968) and Milner and Hills (1968) who used imipramine and Smith and Gonzales (1967) and Lake (1968), who used nortriptyline, b'lit complete control has been unusual and so~e, including 'Fisher et al (1963) and Abrams(1964) have found placebos as useful. Maxwell and Seldrup'(1971) conducted a double blind trail with imipramine, using doses up to 50 mg, and concluded that the benefits of the drug were so well established that they would not hesitate to use it as a' treatment.. They found imiprami~e to be significantly superior to placebo in reducing the number of" wet" nights. Forsythe and Merrett (1969) comparing imipramine and nortiiptylinewith a placebo, found similar benefit. .' ,

Cite this paper

@inproceedings{ENURESIS2011NortriptylineIE, title={Nortriptyline in Enuresis in ' Children with Specif , Ic Gas - Chromatograph Ic Determination O , F Steady - State Serum Levels}, author={NORTRIPTYLINE IN ENURESIS}, year={2011} }