North American Prodrome Longitudinal Study: a collaborative multisite approach to prodromal schizophrenia research.

  title={North American Prodrome Longitudinal Study: a collaborative multisite approach to prodromal schizophrenia research.},
  author={Jean Addington and Kristin S. Cadenhead and Tyrone D. Cannon and Barbara A. Cornblatt and Thomas H. McGlashan and Diana O. Perkins and Larry J. Seidman and Ming T. Tsuang and Elaine F. Walker and Scott W. Woods and Robert K Heinssen},
  journal={Schizophrenia bulletin},
  volume={33 3},
This article presents the rationale, design, and preliminary findings of the North American Prodrome Longitudinal Study (NAPLS), a collaborative, multisite investigation into the earliest phase of psychotic illness. We describe how 8 independently conceived research projects were integrated methodologically, how diagnostic reliability was achieved across sites on the Structured Interview for Prodromal Syndromes, and how baseline and follow-up data were aggregated for 888 at risk and comparison… CONTINUE READING
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