Norovirus capture with histo-blood group antigens reveals novel virus-ligand interactions.

@article{Harrington2004NorovirusCW,
  title={Norovirus capture with histo-blood group antigens reveals novel virus-ligand interactions.},
  author={Patrick R Harrington and J. Vinje and Christine L Moe and Ralph S. Baric},
  journal={Journal of virology},
  year={2004},
  volume={78 6},
  pages={3035-45}
}
Noroviruses are genetically diverse, uncultivable, positive-sense RNA viruses and are the most common cause of epidemic acute gastroenteritis in humans in the United States. Recent studies of norovirus attachment in vitro by using recombinant virus-like particles (VLPs) suggest that various norovirus strains exhibit different patterns of attachment to ABH histo-blood group antigens, which are carbohydrate epitopes present in high concentrations on mucosal cell surfaces of the gut. However… CONTINUE READING

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