Norman Geschwind’s contribution to the understanding of behavioral changes in temporal lobe epilepsy: The February 1974 lecture

  title={Norman Geschwind’s contribution to the understanding of behavioral changes in temporal lobe epilepsy: The February 1974 lecture},
  author={Julie Devinsky and Steven C. Schachter},
  journal={Epilepsy \& Behavior},
Norman Geschwind catalyzed academic interest in the study of interictal behavioral changes in temporal lobe epilepsy. His contributions to this area comprise a series of 11 articles, chapters, editorials, and commentaries published between 1973 and 1984. This article summarizes, both chronologically and by behavioral topic, Geschwind's contributions and opinions on behavioral changes in temporal lobe epilepsy. A previously unpublished lecture (see article in this issue), "Personality Change in… Expand
Norman Geschwind and the Use of History in the (Re)Birth of Behavioral Neurology
  • H. Kushner
  • Psychology, Medicine
  • Journal of the history of the neurosciences
  • 2015
Norman Geschwind urged the resurrection of Wernicke’s disconnection syndromes that he labeled as Behavioral Neurology, discovering a complex and multilayered explanation for aphasias that implicated lesions located in association pathways that, when extensive, resulted in behavioral disorders. Expand
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Cognitive impairments in epilepsy often exist from the commencement of the epilepsy; early-onset lesions/epilepsy interfere with mental development; and a progressive etiology, severe seizures, and lesions secondary to epilepsy can accelerate mental decline. Expand
Specificity of psychopathology in temporal lobe epilepsy
The MMPI-2 scales that resemble descriptions of the Interictal Dysphoric Disorder or Temporal Lobe Epilepsy Personality Syndrome were not elevated in either group of patients with temporal lobe epilepsy compared with the group of Patients with non-temporal lobe epilepsy or heterogeneous neurological controls. Expand
A case of a 36 year old male with a unique presentation of postictal psychosis with interictal hyper religiosity, circumstantial speech that was earlier diagnosed as schizophrenia is presented. Expand
Personality patterns of people with medically refractory epilepsy – Does the epileptogenic zone matter?
People with refractory epilepsy have high rates of dysfunctional personality patterns, which differ according to the epileptogenic zone, and this pattern was a significant predictor of higher scores of the Avoidant and Compulsive personality patterns. Expand
Can different mechanisms underpin the “Geschwind syndrome” in temporal lobe epilepsy and in temporal lobe variant of frontotemporal degeneration?
a Institute of Neurology of the Policlinico Gemelli/ Catholic University of Rome, Italy b IRCCS Fondazione Santa Lucia, Department of Clinical and Behavioral Neurology, Rome, Italy 90 91 92 93 94 95Expand
Cognitive disorders in epilepsy II: Clinical targets, indications and selection of test instruments
This narrative review summarizes the present state of neuropsychological assessments in epilepsy, reveals diagnostic gaps, and shows the great need for education, homogenization, translation and standardization of instruments. Expand
Isolated Hyperreligiosity in a Patient with Temporal Lobe Epilepsy
A 40-year-old man with history of temporal lobe epilepsy presented to the emergency department with hyperreligiosity after medication noncompliance. After medications were resumed, he returned toExpand
Hypersexuality and Neuroimaging Personality, Social Cognition, and Character
Abstract An overview of the complexities of neuroimaging of personality, social cognition, and character (NPSCC) is provided, using hypersexuality (HS) as an example. In Section 1 , many questionsExpand


Behavioural changes in temporal lobe epilepsy.
The behavioural or personality syndrome of temporal epilepsy is a characteristic syndrome of behavioural change which occurs with higher frequency in temporal lobe epilepsy (and possibly in other cases with a spike focus in limbic structures) than in other neurological conditions. Expand
Behnavioral Change in Temporal Lobe Epilepsy
The issue of behavioral change in temporal lobe epilepsy has, to say the least, been the source of fierce argument. Unfortunately one of the major wellsprings of the acrimony has been the failure ofExpand
Quantitative analysis of interictal behavior in temporal lobe epilepsy.
The results support the hypotheses that sensory-affective associations are established within the temporal lobes, and that, in man, there exists a hemispheric asymmetry in the expression of affect. Expand
Reversibility by temporal-lobe resection of the behavioral abnormalities of temporal-lobe epilepsy.
  • M. Falconer
  • Medicine
  • The New England journal of medicine
  • 1973
In patients with schizophrenia, operation relieved epilepsy, but the psychosis persisted, and when a schizophrenia-like state supervenes, the substrate is likely to be a hamartoma. Expand
The interictal behavior syndrome of temporal lobe epilepsy.
The demonstration of interictal spike activity in temporal structures provides a pathophysiologic basis for the behavior syndrome of temporal lobe epilepsy, and may prove to be a useful model in studies on the neural substrates for behavior. Expand
Interictal behavior abnormality in temporal lobe epilepsy. A specific syndrome or nonspecific psychopathology?
  • D. Mungas
  • Psychology, Medicine
  • Archives of general psychiatry
  • 1982
The results of these two studies suggest that previously reported differences between temporal lobe epileptics and normals on these trait variables reflect underlying differences in degree of nonspecific psychopathology and do not necessarily indicate the presence of a specific behavioral syndrome in temporal lobe epilepsy. Expand
Interictal Behavioral Changes in Epilepsy
There is a heightened emotional response to many stimuli as well as a decrease in sexual responsiveness in patients with partial complex seizures, speculated that these behavioral alterations are the result of an intermittent spike focus in the temporal lobe that leads to an alteration in the responsiveness of the limbic system. Expand
Temporal Lobe Epilepsy - A Syndrome Of Sensory-Limbic Hyperconnection
  • D. Bear
  • Psychology, Medicine
  • Cortex
  • 1979
It is suggested that the epileptic process effects sensory limbic hyperconnection, leading to a suffusion of experience with emotional coloration, in contrast to sensory limbics disconnection which results in dissociation of stimuli from affective values. Expand
Hypergraphia in temporal lobe epilepsy
The phenomenon of hypergraphia, or the tendency toward extensive and, in some cases, compulsive writing in temporal lobe epilepsy is described in seven patients, in each of whom there wasExpand
Epilepsy, Personality, Behavior and Psychopathology –The State of the Evidence and Directions for Future Research and Treatment–*
  • J. Stevens
  • Psychology, Medicine
  • Folia psychiatrica et neurologica japonica
  • 1983
The relationship between epilepsy and psychopathology has long interested both neurologists and psychiatrists and the role of natural or normal episodic “excessive neuronal discharge” and the processes that foster or inhibit propagation and synchrony of excessive neuronal discharges from their natural and unnatural sources is focused on. Expand