Normalizing effects of modafinil on sleep in chronic cocaine users.

  title={Normalizing effects of modafinil on sleep in chronic cocaine users.},
  author={Peter T. Morgan and Edward F. Pace-Schott and Brian Pittman and Robert Stickgold and Robert Malison},
  journal={The American journal of psychiatry},
  volume={167 3},
OBJECTIVE The purpose of the present study was to determine the effect of morning-dosed modafinil on sleep and daytime sleepiness in chronic cocaine users. METHOD Twenty cocaine-dependent participants were randomly assigned to receive modafinil, 400 mg (N=10), or placebo (N=10) every morning at 7:30 a.m. for 16 days in an inpatient, double-blind randomized trial. Participants underwent polysomnographic sleep recordings on days 1 to 3, 7 to 9, and 14 to 16 (first, second, and third weeks of… CONTINUE READING

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