Normalizing dopamine D2 receptor-mediated responses in D2 null mutant mice by virus-mediated receptor restoration: comparing D2L and D2S.

@article{Neve2013NormalizingDD,
  title={Normalizing dopamine D2 receptor-mediated responses in D2 null mutant mice by virus-mediated receptor restoration: comparing D2L and D2S.},
  author={Kim A Neve and Christopher P Ford and David C. Buck and David K. Grandy and Rachel L. Neve and Tamara J Phillips},
  journal={Neuroscience},
  year={2013},
  volume={248},
  pages={479-87}
}
D2 receptor null mutant (Drd2(-/-)) mice have altered responses to the rewarding and locomotor effects of psychostimulant drugs, which is evidence of a necessary role for D2 receptors in these behaviors. Furthermore, work with mice that constitutively express only the D2 receptor short form (D2S), as a result of genetic deletion of the long form (D2L), provides the basis for a current model in which D2L is thought to be the postsynaptic D2 receptor on medium spiny neurons in the basal forebrain… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 33 references

Similar Papers

Loading similar papers…