Normalized ultraviolet (UV) induction of Langerhans cell depletion and neutrophil infiltrates after artificial UVB hardening of patients with polymorphic light eruption.

@article{Janssens2005NormalizedU,
  title={Normalized ultraviolet (UV) induction of Langerhans cell depletion and neutrophil infiltrates after artificial UVB hardening of patients with polymorphic light eruption.},
  author={Artiena Soe Janssens and S Zelenovskiy Pavel and Jacoba J. Out-Luiting and Roelof Willemze and Frank R de Gruijl},
  journal={The British journal of dermatology},
  year={2005},
  volume={152 6},
  pages={
          1268-74
        }
}
BACKGROUND Ultraviolet (UV) B hardening has been widely used as a prophylactic treatment in patients with polymorphic light eruption (PLE). Recent investigations have shown that in patients with PLE Langerhans cells (LCs) and neutrophils display less migration from and to the epidermis after an intense UVB irradiation compared with controls. OBJECTIVES To investigate the effect of UVB hardening of patients with PLE on their cell migratory responses after intense UVB exposure. METHODS… CONTINUE READING
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