Normalization of information processing deficits in schizophrenia with clozapine.

  title={Normalization of information processing deficits in schizophrenia with clozapine.},
  author={Veena Kumari and William Soni and Tonmoy Sharma},
  journal={The American journal of psychiatry},
  volume={156 7},
OBJECTIVE The authors tested the hypothesis that the use of an atypical drug, clozapine, for patients with schizophrenia is related to less impairment in information processing deficits (assessed by prepulse inhibition of the startle response) than is the use of typical antipsychotics. METHOD Two groups of schizophrenic patients--receiving either clozapine or a range of typical antipsychotics--were tested for prepulse inhibition (a reduction in response to a starting stimulus, if preceded… CONTINUE READING
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